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Displaying results 2261 - 2270 of 6196 in total
  1. Drug

    Seliforant

    go.drugbank.com/drugs/DB15220
    Investigational

    Seliforant is under investigation in clinical trial NCT01260753 (Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge).

  2. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. … The treatment aims to resolve infection-related symptoms and achieve negative urine culture, where the infections are proven or strongly suspected to be caused by susceptible bacteria.

  3. Drug

    Vortioxetine

    go.drugbank.com/drugs/DB09068
    ApprovedInvestigational

    Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional … agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors.

  4. Drug

    Benzquinamide

    go.drugbank.com/drugs/DB00767
    ApprovedWithdrawn

    The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.

    International brands: Emete-con
  5. Drug

    Rhodotorula rubra

    go.drugbank.com/drugs/DB10442
    Approved

    Rhodotorula rubra is a fungus which can provoke allergic reactions. Rhodotorula rubra is used in allergenic testing.

  6. Drug

    Rhodotorula mucilaginosa

    go.drugbank.com/drugs/DB10701
    Approved

    Rhodotorula mucilaginosa is a fungus which can provoke allergic reactions. Rhodotorula mucilaginosa is used in allergenic testing.

  7. Drug

    Candida tropicalis

    go.drugbank.com/drugs/DB10807
    Approved

    Candida tropicalis is a fungus which can provoke allergic reactions. Candida tropicalis is used in allergenic testing.

  8. Target

    Eukaryotic translation initiation factor 6

    go.drugbank.com/bio_entities/BE0008972
    TargetHumans

    Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm (PubMed:10085284, PubMed:14654845, PubMed:21536732, PubMed:32669547). Behaves as a stimula...

    Synonyms: CAB
  9. Target

    P-type sodium-transporting ATPase4

    go.drugbank.com/bio_entities/BE0009185
    TargetPlasmodium falciparum (isolate 3D7)

    Sodium-exporting ATPase (PubMed:23414762, PubMed:29986883, PubMed:31311978, PubMed:36180431). Required for the extrusion of Na(+) from the intraerythrocytic parasites to maintain a low cytosolic concentration of Na(+) (PubMed:23414762, P...

    Synonyms: Non-SERCA-type Ca2+-transporting P-ATPase
  10. Drug

    Tetrofosmin

    go.drugbank.com/drugs/DB11180
    Approved

    Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.