Search

Displaying results 2271 - 2280 of 10000 in total
  1. Drug

    Lymecycline

    go.drugbank.com/drugs/DB00256
    ApprovedInvestigationalWithdrawn

    [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and efficacy.[A203255] Lymecycline was initially discovered in 1961. … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.

    Synonyms: (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracyclineProducts: XELTETRA-L, TETRALYSAL® CAPSULAS 300 MG
  2. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    The levo-isomer appears to exhibit a very limited antitussive effect. … Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States.

    Mixtures: Darvocet-N 50, Darvocet-N 100Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  3. Drug

    Nilutamide

    go.drugbank.com/drugs/DB00665
    ApprovedInvestigational

    To date, antiandrogen monotherapy has not consistently been shown to be equivalent to castration. … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).

    Categories: Androgen Receptor Antagonists, Androgen Receptor InhibitorsSynonyms: 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoin
  4. Drug

    Valerian

    go.drugbank.com/drugs/DB13196
    Approved

    Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain. … Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

    Mixtures: S. R. Formula, Lapidar 7 TabProducts: Sleep-eze V Natural Caplets
  5. Drug

    Ketamine

    go.drugbank.com/drugs/DB01221
    ApprovedInvestigationalVet approved

    Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]

    Categories: NMDA Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone, 2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
  6. Drug

    Dermatophagoides farinae

    go.drugbank.com/drugs/DB10400
    ApprovedInvestigational

    This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.

    Mixtures: SLITone ULTRA D. pteronyssinus/ D. farinaeProducts: Standardized Mite D Farinae, Standardized Mite D. farinae
  7. Drug

    Dermatophagoides pteronyssinus

    go.drugbank.com/drugs/DB10401
    ApprovedInvestigational

    This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.

    Mixtures: SLITone ULTRA D. pteronyssinus/ D. farinaeProducts: Standardized Mite D Pteronyssinus, Standardized Mite D. pteronyssinus
  8. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position. … [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: UROMAX® 1000MG/4 ML SOLUCIÓNINYECTABLE, NEBIDO ®
  9. Drug

    Garetosmab

    go.drugbank.com/drugs/DB16379
    ApprovedInvestigational

    [L63940] It is a fully human IgG4 monoclonal antibody that binds and neutralizes activin A, blocking activin A from activating the mutant ACVR1 receptor that, in FOP, drives the formation of heterotopic … Garetosmab-grts is an activin A inhibitor used to treat fibrodysplasia ossificans progressiva (FOP).

  10. Drug

    D-glucose

    go.drugbank.com/drugs/DB01914
    ApprovedInvestigationalVet approved

    L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants.

    Synonyms: D-glucose, D(+)-GlucoseSalts: D-glucose monohydrate