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Displaying results 2271 - 2280 of 10000 in total
  1. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    It may cause a superinfection with gram-positive organisms. … A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum.

    Synonyms: 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid, (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acidCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Milnacipran

    go.drugbank.com/drugs/DB04896
    ApprovedInvestigational

    Nevertheless, milnacipran demonstrates a somewhat unique characteristic among SNRIs to elicit a relatively balanced reuptake inhibition of both serotonin and noradrenaline, with a somewhat increased preference … (BACE-1), which has investigationally been associated with β-amyloid plaque formation - making the agent a possible course of treatment for Alzheimer's disease [A175957].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: Ixel 25 mg - Kapseln, Ixel 50 mg - Kapseln
  3. Drug

    Decitabine

    go.drugbank.com/drugs/DB01262
    ApprovedInvestigational

    [A2263, A2264, A2265, A215317, L14962] Decitabine was developed by MGI Pharma/SuperGen Inc. and was approved by the FDA for the treatment of MDS on February 5, 2006. … Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.

    Synonyms: 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one, 5-aza-2'-deoxycytidineCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Phellodendron amurense bark

    go.drugbank.com/drugs/DB14370
    Investigational

    Phellodendron amurense bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: Jayeonbi Secret Care Mist for Lady Y-zone Mist, Jayeonbi Secret Care Mist for Men Y-zone Mist
  5. Drug

    Potassium nitrate

    go.drugbank.com/drugs/DB11090
    ApprovedInvestigational

    In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. It is administered orally doses up to 30 g per animal per day [L1736]. … Potassium nitrate is an inorganic salt with a chemical formula of KNO3.

    Mixtures: Hapee Gumtect Sensitive 100, SENSORAL 250 ML SOLUSYONCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Medronic acid

    go.drugbank.com/drugs/DB14078
    ApprovedInvestigational

    Products: MON MDP KIT 10 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET, DRAXIMAGE® MDP
  7. Indication

    Perioperative Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089513
    Drugs: Anti-inhibitor coagulant complex
    Synonyms: Perioperative Bleeding caused by Hemophilia A
  8. Drug

    Carvedilol

    go.drugbank.com/drugs/DB01136
    ApprovedInvestigational

    Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. … [L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the

    Synonyms: (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanolMixtures: Co-Dilatrend 25 mg/12,5 mg - Filmtabletten, CARIVALAN 25/5
  9. Drug

    Dronedarone

    go.drugbank.com/drugs/DB04855
    ApprovedInvestigational

    [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009. … A safety concern for the risk of drug-induced hepatocellular injury has been issued following marketing of dronedarone.[L8800]

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide
  10. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. … The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007.

    Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsProducts: PERGOLID-NEURAX 1 MG, PERGOLID-NEURAX 0.25 MG