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Displaying results 2271 - 2280 of 10000 in total
  1. Drug

    Pyrimethamine

    go.drugbank.com/drugs/DB00205
    ApprovedInvestigationalVet approved

    One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
  2. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. … [A263481] Sotatercept was approved by the European Commission on August 26, 2024.[L51549]

    Synonyms: (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-Categories: Immunoglobulin G
  3. Drug

    Remestemcel-L

    go.drugbank.com/drugs/DB13973
    ApprovedInvestigationalWithdrawn

    of the recipients [A31818]. aGvHD is often characterized by the presence of inflammatory cascades through signalling of activated T cells. … It is estimated that the patients with the most severe forms of refractory aGvHD that do not respond to steroid therapy have expected one-year survival rates of only 5% to 30% [L11022].

    Synonyms: Remestemcel-L
  4. Drug

    Potassium hydroxide

    go.drugbank.com/drugs/DB11153
    Approved

    Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. … Potassium hydroxide, also known as _lye_ is an inorganic compound with the chemical formula _KOH_.

    Mixtures: Vamin N, Kalium-L-malat "Fresenius" 1 molar - Infusionszusatz - AmpullenCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Lanreotide

    go.drugbank.com/drugs/DB06791
    ApprovedInvestigational

    This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. … Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SOMATULINE ® AUTOGEL ® 60 MG, Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg
  6. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.

    Synonyms: 3-Hydroxy-1,3,5(10)-estratrien-17-oneCategories: Sex Hormones and Modulators of the Genital System, P-glycoprotein inducers
  7. Drug

    Bendroflumethiazide

    go.drugbank.com/drugs/DB00436
    ApprovedInvestigational

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)

    Synonyms: ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxideMixtures: Corzide Tab W Nadolol 80mg, Corzide Tab W Nadolol 40mg
  8. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation … the risk of colorectal cancer in conditions like ulcerative colitis is maintained.

    Synonyms: 3-carboxy-4-hydroxyaniline, 5-ASAProducts: PENTASA®1 G GRANULOS DE LIBERACION PROLONGADA, PENTASA® GRANULOS DE LIBERACION PROLONGADA 2 G
  9. Drug

    Homatropine

    go.drugbank.com/drugs/DB11181
    Approved

    Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic … Homatropine is included in subtherapeutic amounts as homatropine methylbromide to discourage deliberate overdosage.

    Products: HOMATRO 2%, Isopto Homatropine 2%
  10. Drug

    Menotropins

    go.drugbank.com/drugs/DB00032
    ApprovedInvestigational

    Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. … It is used as a fertility medication that is injected either subcutaneously or intramuscularly.

    Categories: Sex Hormones and Modulators of the Genital System