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Fimaporfin
go.drugbank.com/drugs/DB17253InvestigationalSynonyms: 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and c (25%, 50%, 25%)Protein S human
go.drugbank.com/drugs/DB13149ApprovedInvestigationalProtein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561]. It serves as a negative feedback mechanism in the coagulation cascade.
Synonyms: Vitamin K-dependent protein S, Protein SMixtures: COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETNaloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalNaloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. … It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsSynonyms: (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diolMetabolism and Physiological Effects of Phenylacetic Acid
smpdb.ca/view/SMP0123256MetabolicPhenylacetic acid is carboxylic acid ester that has also been found to be a uremic toxin that is synthesized from L-phenylalanine. L-Phenylalanine is consumed through high protein foods such as eggs, chicken, liver, beef, milk, and soybe...
Enzymes: Y+L amino acid transporter 1Birch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational[L42365,L42370] Filsuvez, one of these two formulations, is approved for the treatment of partial thickness wounds in patients with epidermolysis bullosa (EB), a rare group of hereditary disorders of the … [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTilidine
go.drugbank.com/drugs/DB13787InvestigationalMixtures: VALORON N RETARD 50/4MG, VALORON N RETARD 50/4MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalat half (50 mcg) of its regular strength. … [L39307] The Moderna COVID-19 vaccine is also approved for use as a fourth booster shot in adults 50 years of age and older.
Synonyms: MRNA-1273 SARS-COV-2Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Pralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigationalIt is currently marketed under the brand name GAVRETO™ by Blueprint Medicines.[L15986] … [A202049, A202055, L15986] Although a phase 1/2 trial of pralsetinib termed ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, 2020, for the treatment
Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 SubstratesArdeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnIts molecular weight ranges from 2000 to 15,000 with an average molecular weight of 5500 to 6500. Normiflo was withdrawn from the US market in March 2000. … Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis.
Chlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Mixtures: Supres 250 Tab, Supres 150 TabCategories: Heterocyclic Compounds, 2-Ring, Genito Urinary System and Sex Hormones