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Propofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. … Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: PROPOFOL-PF %1 200 MG/20 ML I.V. ENJEKSİYONLUK/İNFÜZYONLUK EMÜLSİYON, 5 ADET, FRESOFOL 2% MCT/LCT EMULSION FOR INJECTION OR INFUSIONCeftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigationalBacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibio...
Mixtures: CEFAZIME FOR INJECTION 1 g/vialCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalIn Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions … Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties.
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 SubstratesProducts: Mar-dienogestFibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalIt is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … It is indicated for the treatment of acute bleeding episodes in patients with both acquired and congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.[L41065]
Mixtures: SAN. VE TİC. LTD., BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICIProducts: HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL, Haemocomplettan P 1g/2g Pulver zur Herstellung einer Injektions-/InfusionslösungHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 1...
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Corticosteroids for Systemic UseProducts: Family Wellness Max Strength 1 Hydrocortisone Cream, Meijer Max. Strength Anti-Itch Cream Intensive Healing FormulaAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … However, its use for the treatment of acute ischemic stroke (AIS) has increased over the years.
Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PATividenofusp alfa
go.drugbank.com/drugs/DB17628ApprovedInvestigationalTividenofusp alfa is a recombinant human IDS fused to a monoclonal antibody that targets the human insulin receptor (HIR), utilizing receptor-mediated transcytosis to gain access to the central nervous … Tividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099
Synonyms: -bis(disulfide) with immunoglobulin Fcab anti-(human type 1 transferrin receptor) (synthetic hu, ENZYME TRANSPORT VEHICLE SPECIFIC FOR THE TRANSFERRIN RECEPTOR FUSED TO IDURONATE 2-SULFATASELevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigational. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration.
Mixtures: HO YAN HOR MEDICATED OIL, Huo Pao Tieh Ta Feng Shin KaoCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approvedClindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Clindacin P, CLINDAMYCIN - CT 300MG KAPMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Astramorph PF, MORPHIN HEXAL 10MG RET KAP