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Adapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigational[A193518] Adapalene has similar efficacy but a superior safety profile compared to tretinoin. … [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women.
Categories: Anti-Acne Preparations for Topical Use, Retinoids for Topical Use in AcneProducts: Adapalene Gel USP, 0.3%Tadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH.
Products: TADAFIL 5 TADALAFIL TABLETS USP 5 MG, TALIS 20 - TADALAFIL TABLETS USP 20MGAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalIn 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men … This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth.
Products: Alprostadil Injection USP, Alprostadil Injection, USPNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approveda greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate for systemic use … [L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly
Categories: Antifungals for Topical Use, Antibacterials for Systemic UseProducts: Jamp-nystatin Oral Suspension USP, Nyaderm Oral Sus 100000unit/ml USPMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalUse of OAT is also intended to lead to social stabilization by reducing crime rates, incarceration, use of illicit opioids such as [heroin] or [fentanyl], and ultimately marginalization. … Provision of OAT is often combined with education about harm reduction including use of clean needles and injection supplies in an effort to reduce the risks associated with injection drug use such as
Products: Methadone Hydrochloride Oral Concentrate USPImiquimod
go.drugbank.com/drugs/DB00724ApprovedInvestigationalImiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear ...
Products: Imiquad Cream (Imiquimod Cream USP 5% w/w)Ondansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawnHaving been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has demonstrated a long history of use and efficacy. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.
Products: Ondansetron Injection USP, Ondansetron Injection, USPAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedInterestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes.
Mixtures: Spasmhalt-asa-8, Asa and CaffeineSynonyms: ASANorepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalPrecursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter.
Products: Norepinephrine Bitartrate Injection USP, Norepinephrine Bitartrate Injection, USPPrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Products: Prednisolone Acetate Ophthalmic Suspension USP 1%