Search

Displaying results 221 - 230 of 10000 in total
  1. Drug

    Mirdametinib

    go.drugbank.com/drugs/DB07101
    ApprovedInvestigational

    [A265065] Mirdametinib selectively and potently inhibits the MEK1/2 enzymes.[A265065] … Mirdametinib is a mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor. On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1).

    Categories: P-glycoprotein substratesSynonyms: N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDE, (-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE
  2. Drug

    Cysteamine

    go.drugbank.com/drugs/DB00847
    ApprovedInvestigational

    Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. … [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis.

    Synonyms: 2-amino-1-ethanethiol, 2-aminoethanethiolProducts: CYSTAGON ® 150 MG, CYSTADROPS® 3.8 MG/ML SOLUCIÓN OFTÁLMICA
  3. Drug

    Propylthiouracil

    go.drugbank.com/drugs/DB00550
    Approved

    A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine.

    Synonyms: 4-propyl-2-thiouracil, 2-Mercapto-6-propyl-4-pyrimidoneCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Methapyrilene

    go.drugbank.com/drugs/DB04819
    ApprovedWithdrawn

    Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine, N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamine
  5. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.

    Mixtures: CAPOZIDE 50/25 MG TABLETAS, CAPTOBETA 25/25 COMPCategories: P-glycoprotein inhibitors
  6. Drug

    N(2)-(2-carboxyethyl)-L-arginine

    go.drugbank.com/drugs/DB04189
    Experimental

    Synonyms: N(2)-(2-carboxyethyl)-L-arginine, L-N2-(2-Carboxyethyl)arginine
  7. Drug

    TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE

    go.drugbank.com/drugs/DB08594
    Experimental

    Synonyms: TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE
  8. Drug

    5-(2-NITROPHENYL)-2-FUROIC ACID

    go.drugbank.com/drugs/DB07408
    Experimental

    Synonyms: 5-(2-NITROPHENYL)-2-FUROIC ACID
  9. Drug

    2-Ethylhexyl 4-phenylbenzophenone-2'-carboxylate

    go.drugbank.com/drugs/DB14471
    Experimental

  10. Drug

    Oxymetazoline

    go.drugbank.com/drugs/DB00935
    ApprovedInvestigational

    Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [A215542] Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults.

    Synonyms: 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenolInternational brands: Dristan 12-Hour, Neo-Synephrine 12 Hour Spray