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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Chlorzoxazone

    go.drugbank.com/drugs/DB00356
    Approved

    A centrally acting central muscle relaxant with sedative properties. … It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

    Synonyms: 5-chloro-2-benzoxazolol, 5-chloro-2-benzoxazolinoneInternational brands: Remular-S
  2. Drug

    Poliovirus type 1 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10795
    ApprovedInvestigational

    Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line of monkey kidney cells.

    Synonyms: poliovirus vaccine inactivated, type 1 (Mahoney), Poliovirus type 1 antigen (formaldehyde inactivated)Mixtures: Dt Polio Adsorbed - Sus Im, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET
  3. Drug

    1-Deoxy-D-xylulose 5-phosphate

    go.drugbank.com/drugs/DB02496
    Experimental

    The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate … 1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.

    Synonyms: 1-Deoxy-D-xylulose 5-phosphate
  4. Drug

    Oteseconazole

    go.drugbank.com/drugs/DB13055
    ApprovedInvestigational

    [L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. … [A247035] In contrast with oteseconazole, other antifungals with imidazole or triazole moieties, such as [ketoconazole] or [fluconazole], have a high number of drug-drug interactions due to their interaction

    Categories: Heterocyclic Compounds, 1-Ring, 14-alpha Demethylase InhibitorsSynonyms: (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, 2-Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl)-,(αR)
  5. Drug

    Linoleic acid

    go.drugbank.com/drugs/DB14104
    Approved

    Mixtures: Evening Primrose Oil Cap 500mg W Vit E, Huile D'onagre Vitamin ECategories: Fatty Acids, Omega-6
  6. Drug

    1-(5-phospho-D-ribosyl)-ATP

    go.drugbank.com/drugs/DB01661
    Experimental

    Synonyms: 1-(5-phospho-D-ribosyl)-ATPCategories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Aminophenazone

    go.drugbank.com/drugs/DB01424
    ApprovedWithdrawn

    The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942] … Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis.

    Categories: Heterocyclic Compounds, 1-Ring, Non COX-2 selective NSAIDSSynonyms: 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone, 1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one
  8. Drug

    1-Amino-2,3-Dihydroxy-5-Hydroxymethyl Cyclohex-5-Ene

    go.drugbank.com/drugs/DB01789
    Experimental

    Synonyms: 1-Amino-2,3-Dihydroxy-5-Hydroxymethyl Cyclohex-5-Ene
  9. Drug

    Levobunolol

    go.drugbank.com/drugs/DB01210
    Approved

    A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.

    Synonyms: (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  10. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. … In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 5 InhibitorsSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide