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Edaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigational[L44007] The oral suspension formulation of edaravone was approved by the FDA in May 2022 and by Health Canada in November 2022. … [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and South Korea in 2015, followed by the FDA approval in May 2017 [L41810] and Health Canada approval in
Products: RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mLDaclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnIt is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . … The most common critical NS5A amino acid substitutions that led to reduced susceptibility to daclatasvir therapy occured at position Q30 (Q30H/K/R) and M28 in genotype 1a patients and Y93H in genotype
Categories: Amino Acids, Peptides, and Proteins, daclatasvir, asunaprevir and beclabuvirProducts: DAKLINZA TABLET 30MG, DAKLINZA TABLET 60MGIndalpine
go.drugbank.com/drugs/DB08953ApprovedWithdrawnHowever, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market. … It was initially marketed by Pharmuka.
Scopolamine
go.drugbank.com/drugs/DB00747ApprovedInvestigational[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. … Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine
Mixtures: Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide, Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine HydrobromideCategories: Hypnotics and Sedatives, Alimentary Tract and MetabolismGlucarpidase
go.drugbank.com/drugs/DB08898ApprovedInvestigationalfrom _Pseudomonas stutzeri_ in 1967. … [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approved[A32011] Many bacteria, like _Leuconostoc_, can synthesize dextran from sucrose, and this activity is used commercially to obtain dextran. … It is produced from certain bacteria that with α-1,6 glycosidic linkages between glucose molecules and α-1,3 linkages between branches.
Mixtures: Redness reliever and Lubricant, Meijer Advanced Redness and Irritation ReliefCategories: Blood and Related Products, Blood and Blood Forming OrgansCupric oxide
go.drugbank.com/drugs/DB11134ApprovedThey may also be produced from electronic wastes. Cupric oxide poses potential health and environmental concern due to toxic and mutagenic particles generating reactive oxygen species [A32656]. … Copper(II) oxide nanoparticles (NPCuO) have industrial applications as antimicrobial agents in textiles and paints, and catalysts in organic synthesis [A32656].
Mixtures: Prenatal Vitamin-mineral Supplement Folic 5mg, Multivitamin and MineralCategories: Diet, Food, and NutritionPropoxycaine
go.drugbank.com/drugs/DB09342ApprovedThis drug was removed from the US market in 1996. … Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride [L1588].
WP-1122
go.drugbank.com/drugs/DB17192InvestigationalWP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Synonyms: an acetic acid diester of 2-deoxy-D-glucoseBlood Transfusion Complications
go.drugbank.com/conditions/DBCOND0086922Synonyms: Dyspnea due to and following transfusion, Dyspnoea due to and following transfusion