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Ancrod
go.drugbank.com/drugs/DB05099ApprovedWithdrawnand oxygen to portions of the brain, for which phase III trials are currently being conducted. … Currently, Viprinex®/ancrod is not approved or marketed in any country, but is being investigated as a stroke treatment in worldwide clinical trials. In January 2005, the U.S.
Methocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approved[A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts … Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether.
Mixtures: Soulagement Des Douleurs Musculaires & Courbatures Extra Fort, Douleurs Musculaires Et Les Courbatures Extra Fort/muscle and Back Pain Relief Extra StrengthAlmasilate
go.drugbank.com/drugs/DB13595ApprovedHowever its therapeutic efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and binding bile salts than other conventional antacids [A27138]. … It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer.
Categories: Drugs for Acid Related DisordersAmmonia N-13
go.drugbank.com/drugs/DB09326ApprovedAmmonia N 13 Injection, USP is used for imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease … Ammonia N 13 Injection, USP is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.
Xenon-133
go.drugbank.com/drugs/DB09315ApprovedXenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess pulmonary function.
Paritaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationalParitaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … burden compared to older agents such as [DB08873], [DB05521], [DB00008], [DB00022], and [DB00811].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine]. … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria.
Categories: Experimental Unapproved Treatments for COVID-19Trimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate. … Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ).
Categories: Antihistamines for Systemic UseLumacaftor
go.drugbank.com/drugs/DB09280ApprovedInvestigational[A20343] Improvements in lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% of patients failing to achieve an absolute … Approved for use by the Food and Drug Administration in July 2015 and by Health Canada in January 2016, Orkambi was the first combination product approved for the management of Cystic Fibrosis with delta-F508
Ancestim
go.drugbank.com/drugs/DB09103ApprovedWithdrawnAncestim was developed by Amgen and sold to Biovitrium in December 2008. It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes. … It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal