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Displaying results 2291 - 2300 of 4190 in total
  1. Drug

    Butropium

    go.drugbank.com/drugs/DB15968
    Experimental

  2. Drug

    LB-001

    go.drugbank.com/drugs/DB17685
    Experimental

    LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.

  3. Drug

    AP103

    go.drugbank.com/drugs/DB18234
    Experimental

    AP103 is a non-viral gene therapy that uses a delivery vector, HPAE (Highly Branched Poly β-Amino Ester), to deliver the correct collagen VII gene into skin cells.

  4. Drug

    EPC2407

    go.drugbank.com/drugs/DB05189
    Investigational

    EPC2407 is a novel small molecule vascular disruption agent and apoptosis inducer for the treatment of patients with advanced solid tumors and lymphomas. It is intended for the treatment of advanced cancer patients with solid tumors that...

  5. Target

    Ras-related C3 botulinum toxin substrate 1

    go.drugbank.com/bio_entities/BE0001109
    TargetHumans

    Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocy...

    Synonyms: Cell migration-inducing gene 5 protein
  6. Target

    DNA helicase/primase

    go.drugbank.com/bio_entities/BE0001811
    TargetEnterobacteria phage T7

    ATP-dependent DNA helicase and primase essential for viral DNA replication and recombination (PubMed:21606333, PubMed:22977246, PubMed:32009150). The helicase moves 5' -> 3' on the lagging strand template, unwinding the DNA duplex ahead ...

    Synonyms: Gene product 4
  7. Drug

    Umifenovir

    go.drugbank.com/drugs/DB13609
    Investigational

    [A191475] It has been in use in Russia for approximately 25 years and in China since 2006.

  8. Drug

    Promestriene

    go.drugbank.com/drugs/DB12487
    Investigational

    treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like effects on cell proliferation and estrogen-responsive gene … It has been also studied in phase III of the clinical trial in the post-operative patients with hypospadias.

  9. Drug

    Cusatuzumab

    go.drugbank.com/drugs/DB15100
    Investigational

    An overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety of solid and hematological malignancies.

  10. Drug

    LGD-1550

    go.drugbank.com/drugs/DB05785
    Experimental

    LGD-1550 is an orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities.