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Aripiprazole lauroxil
go.drugbank.com/drugs/DB14185ApprovedThe patients may receive Aristada Initio in combination with a single 30 mg oral dose of aripiprazole to achieve appropriate levels of aripiprazole more rapidly. … It is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors [A34289].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: Rose Hips 500plus Nu Life, DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADETSynthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedHowever, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … Conjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives.
Synonyms: Estrogens, Conjugated Synthetic A, Synthetic Conjugated Estrogens, ACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedSodium hydroxide is generally used as a solid or a diluted in a 50% solution. This chemical is used to manufacture soaps, rayon, paper, explosives, dyestuffs, and petroleum products [L1965]. … According to the the FDA, sodium hydroxide is considered a direct food recognized as safe, where it serves as a pH control agent and follows good manufacturing guidelines [L1967].
Mixtures: CLINDAMICINA 600 MG / 4 ML SOLUCIÓN INYECTABLE, NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1250 MLCategories: Compounds used in a research, industrial, or household settingDL-dimyristoylphosphatidylglycerol
go.drugbank.com/drugs/DB11284ApprovedDL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Synonyms: DL-dimyristoylphosphatidylglycerolUridine triacetate
go.drugbank.com/drugs/DB09144Approvedde novo pyrimidine biosynthetic pathway. … By pre-administering with uridine (as the prodrug uridine triacetate), higher doses of 5-FU can be given allowing for improved efficacy and a reduction in toxic side effects [A18578].
Nogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigational[A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … Nogapendekin alfa is a human IL-15N72D variant.
Categories: Interleukin-15, Receptors, Interleukin-15Synonyms: Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform), Il-15n72d:il-15rec-su/fc soluble complex iLM-030
go.drugbank.com/drugs/DB18283InvestigationalSynonyms: (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL)-21-HYDROXY-5-(4-HYDROXY-BENZYL)-15-ISOBUTYL-4,11-DIMETHYL-3,6,9,13,16,22-HEXAOXO-10-OXA-1,4,7,14,17Zavegepant
go.drugbank.com/drugs/DB15688ApprovedInvestigationalof oral zavegepant (150 mg bid) in subjects with mild allergic asthma. … Zavegepant is a third-generation CGRP receptor antagonist that is small in size and highly soluble. Due to its pharmacological properties, it can be administered intranasally.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCyclin-dependent kinase 15
go.drugbank.com/bio_entities/BE0000437TargetHumansSerine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'
Polypeptides: Cyclin-dependent kinase 15Synonyms: Cell division protein kinase 15