Hesperidin

DB04703ApprovedInvestigationalSmall molecule

Hesperidin is a bioflavonoid found in a variety of nutritional supplements that is touted to have various beneficial effects on blood vessel disorders and various other conditions. Hesperidin is a flavan-on glycoside found in citrus fruits.

Chemical structure of Hesperidin
Formula / weight
C28H34O15 · 610.5606 g/mol (avg)
First approval
Canada, 1963
Also known as
Cirantin · Ciratin · Hesperetin 7-O-rutinoside · Hesperidoside
Code names
NDI 590 · NSC-44184

Resolves to

Compound
UNIIE750O06Y6OCAS520-26-3ChEMBLCHEMBL449317ChEBI28775PubChem10621KEGGD01038
Clinical / RWD
RxNorm5281PharmGKBPA449867
Structure
InChIKeyQUQPHWDTPGMPEX-QJBIFVCTSA-NSMILESCOC1=CC=C(C=C1O)[C@@H]1CC(=O)C2=C(O1)C=C(O[C@@H]1O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]1O)C=C2O
Targets
Q00975CACNA1BQ96GD4AURKB

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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27Clinical trialsPhase, status and sponsor resolved per trial
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3Structured indicationsCondition, population, route and combination as fields, not prose
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63Marketed productsAcross 9 countries and 42 labellers
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Hesperidin, and which of those have an active Phase 3 trial?

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