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Heparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalUnfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibl...
Products: Hep-Lock U/P, HEPARIN NA BRA 25000IE IILCorticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedCorticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersInsulin glulisine
go.drugbank.com/drugs/DB01309ApprovedInsulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenous...
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersTolevamer
go.drugbank.com/drugs/DB01344ApprovedSodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical ...
Products: <p>KALQUEST® Powder for Oral Suspension 5g/sachet</p>Poloxamer 407
go.drugbank.com/drugs/DB11252InvestigationalPoloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. P...
Categories: P-glycoprotein inhibitorsNonivamide
go.drugbank.com/drugs/DB11324ApprovedNonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus no...
Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedPoloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsChloroform
go.drugbank.com/drugs/DB11387ApprovedVet approvedWithdrawnChloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigeran...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesEnrofloxacin
go.drugbank.com/drugs/DB11404InvestigationalVet approvedEnrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylob...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsFenbendazole
go.drugbank.com/drugs/DB11410InvestigationalVet approvedFenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, ae...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates