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Displaying results 2301 - 2310 of 10000 in total
  1. Drug

    4-Methylimidazole

    go.drugbank.com/drugs/DB03385
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4(5)-methylimidazole, 4-MEI
  2. Drug

    Tideglusib

    go.drugbank.com/drugs/DB12129
    ApprovedInvestigationalWithdrawn

    It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3).

    Categories: Heterocyclic Compounds, 1-Ring, Glycogen Synthase Kinase 3, antagonists & inhibitorsSynonyms: 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE, 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione
  3. Drug

    Tacrine

    go.drugbank.com/drugs/DB00382
    ApprovedWithdrawn

    A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous

    Synonyms: 5-amino-6,7,8,9-tetrahydroacridine, 1,2,3,4-tetrahydro-9-acridinamineCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  4. Drug

    WNT-974

    go.drugbank.com/drugs/DB12561
    Investigational

    WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (2,4'-bipyridine)-5-acetamide, 2',3-dimethyl-N-(5-(2-pyrazinyl)-2-pyridinyl)-
  5. Drug

    Cyclic GMP

    go.drugbank.com/drugs/DB02315
    Experimental

    Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. … It is a cellular regulatory agent and has been described as a second messenger.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic GMP, Guanosine 3',5'-cyclic phosphate
  6. Drug

    A-674563

    go.drugbank.com/drugs/DB08568
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine
  7. Drug

    HUB-101

    go.drugbank.com/drugs/DB18656
    Experimental

    Synonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene
  8. Drug

    Azelaprag

    go.drugbank.com/drugs/DB19329
    Investigational

    Azelaprag is under investigation in clinical trial NCT06515418 (Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared With Tirzepatide Alone in Participants With Obesity Aged 55 Years

    Synonyms: 2-pyrimidineethanesulfonamide, n-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4h-1,2,4-triazol-3-yl)-.alpha.,.beta.,5-trimethyl-, (.alpha.s,.beta.r)-
  9. Drug

    Eperisone

    go.drugbank.com/drugs/DB08992
    Investigational

    Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and … It is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.

    Synonyms: (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Danicamtiv

    go.drugbank.com/drugs/DB18962
    Investigational

    Danicamtiv is under investigation in clinical trial NCT04572893 (Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities).

    Synonyms: 1-piperidinecarboxamide, 4-((1r)-1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-3-isoxazolyl-, 4-((1r)-1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(1,2-oxazol-3-yl)piperidine-1-carboxamide