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Nateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). … Meglitnides may have a neutral effect on weight or cause a slight increase in weight.
Pheniprazine
go.drugbank.com/drugs/DB09250ApprovedWithdrawnIn addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalIt is indicated for the symptomatic treatment of benign prostatic hyperplasia in adults. … to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for
AVI-4557
go.drugbank.com/drugs/DB05447ExperimentalAVI-4557 is therefore indicated to limit toxicity for patients receiving highly-toxic therapeutic drugs for treatment of anxiety, cancer, and a number of other serious conditions. … AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently
Iophendylate
go.drugbank.com/drugs/DB01187ApprovedIophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. … Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231).
Categories: Compounds used in a research, industrial, or household settingMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Categories: Antidepressive Agents Indicated for DepressionDroxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalIt is approved for use in Japan and is currently in trials in the U.S. … Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is
Tannic acid
go.drugbank.com/drugs/DB09372ApprovedInvestigationalNowadays, tannic acid is applied topically for the treatment of cold sores, diaper rash, fever blisters and poison ivy. … Tannic acid is also taken by mouth and applied directly for bleeding, chronic diarrhea, dysentery, bloody urine, painful joints, persistent coughs, and cancer.
Categories: Compounds used in a research, industrial, or household settingDiethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedEvery year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme disease and Rocky Mountain
Categories: Compounds used in a research, industrial, or household setting