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Vancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalIt is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and enterocolitis
Categories: Alimentary Tract and Metabolism, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Vancocin 1 g - Pulver für ein Konzentrat zur Herstellung einer Infusionslösung und einer Lösung zum Einnehmen, Vancocin 500 mg - Pulver für ein Konzentrat zur Herstellung einer Infusionslösung und einer Lösung zum EinnehmenProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedPharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.
Synonyms: (S)-4-Pregnene-3,20-dione, (S)-Pregn-4-en-3,20-dioneMixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%, Estradiol and ProgesteroneTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. … This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription.
Mixtures: Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20%, Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1%Categories: Skin and Mucous Membrane Agents, Antineoplastic and Immunomodulating AgentsFallypride F-18
go.drugbank.com/drugs/DB19254InvestigationalFallypride F-18 is under investigation in clinical trial NCT00846040 (Reduced Carbohydrate Versus Fat in Obese Subjects).
Synonyms: Benzamide, 5-(3-(fluoro-18f)propyl)-2,3-dimethoxy-n-(((2s)-1-(2-propen-1-yl)-2-pyrrolidinyl)methyl)-, F-18 fallypridePiracetam
go.drugbank.com/drugs/DB09210ApprovedWithdrawnPiracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. … It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA).
Categories: Heterocyclic Compounds, 1-Ring, Psychostimulants, Agents Used for ADHD and NootropicsProducts: SETROPİL 1 G/ 5 ML İ.V. ÇÖZELTİ İÇEREN AMPUL, 12 ADET, NOROTROP 1 GR/5 ML IM/IVAMPUL, 12 ADETVeru-111
go.drugbank.com/drugs/DB16462InvestigationalThese trials aimed to evaluate its efficacy, safety, and tolerability in conditions such as SARS-CoV-2 infection, metastatic castration-resistant prostate cancer (mCRPC), respiratory distress syndrome … in adults, and metastatic triple-negative breast cancer.
Synonyms: Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, [2-(1H-indol-3-yl)-1H-imidazol-4-yl](3,4,5-trimethoxyphenyl)methanoneCategories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Alendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Synonyms: 4-amino-1-hydroxybutane-1,1-diphosphonic acid, (4-amino-1-hydroxybutylidene)bisphosphonic acidMixtures: BONYL 70 MG/2800 IU TABLET, 12 ADET, BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADETFluticasone propionate
go.drugbank.com/drugs/DB00588ApprovedInvestigationalFluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990[L5962].
Mixtures: FLUTIFORM® 250 MCG / 10 MCG, FLUTIFORM® 250 MCG / 10 MCGCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCilofexor
go.drugbank.com/drugs/DB15168InvestigationalCilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Synonyms: 2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acidCategories: Heterocyclic Compounds, 1-RingMethylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approved[L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression. … Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s.
Synonyms: 1-dehydro-6α-methylhydrocortisone, delta(1)-6alpha-MethylhydrocortisoneMixtures: Physicians EZ Use M-pred, Physicians EZ Use M-pred