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Displaying results 2311 - 2320 of 10000 in total
  1. Drug

    Tafasitamab

    go.drugbank.com/drugs/DB15044
    ApprovedInvestigational

    [L15292,A191829] The CD19 surface protein is highly expressed on the surface of B-cells, where it appears to play a role in enhancing B-cell receptor signaling. … for the treatment of relapsed or refractory DLBCL in adult patients who cannot receive autologous stem cell transplants.

  2. Drug

    Phenyl trimethicone

    go.drugbank.com/drugs/DB11313
    Approved

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Dichromate

    go.drugbank.com/drugs/DB14182
    Approved

    Synonyms: Dichromate ion, dichromate ion(2−)Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Debrisoquine

    go.drugbank.com/drugs/DB04840
    Approved

    Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. … An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme.

  5. Drug

    Voretigene neparvovec

    go.drugbank.com/drugs/DB13932
    ApprovedInvestigational

    [A31478] VN-rzyl was developed by Spark Therapeutics Inc. and FDA approved on December 19, 2017.[L1095] … When used in genetic therapy, this virus is modified for the elimination of its negligible integrative capacity by the removal of *rep* and *cap* and the insertion of the desired gene with its promoter

    Synonyms: VN-rzyl
  6. Drug

    Trypsin

    go.drugbank.com/drugs/DB11237
    ApprovedInvestigationalVet approved

    Trypsin also contains an oxyanion hole that stabilizes the charge negative charge on the carbonyl oxygen atom formed from the cleavage of peptide bonds. … Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is intended to aid in digestion when administered orally.

    Categories: Preparations for Treatment of Wounds and Ulcers
  7. Drug

    Oxacillin

    go.drugbank.com/drugs/DB00713
    ApprovedInvestigational

    An antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.

    International brands: Dicloxal Ox, Staficilin-NCategories: combinations of penicillins
  8. Drug

    Relacorilant

    go.drugbank.com/drugs/DB14976
    ApprovedInvestigational

    in the context of resistant cancers. … [L56089] Relacorilant was approved by the US FDA on March 25, 2026, for use in combination with [paclitaxel] in patients with certain platinum-resistant cancers.[L56093,L56089]

  9. Drug

    Maprotiline

    go.drugbank.com/drugs/DB00934
    Approved

    Maprotiline is effective at reducing symptoms of anxiety associated with depression. … It differs from TCAs in that it does not appear to block serotonin reuptake.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Non-Selective Monoamine Reuptake Inhibitors
  10. Drug

    Aminophenazone

    go.drugbank.com/drugs/DB01424
    ApprovedWithdrawn

    The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942] … Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis.

    Synonyms: 1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one, 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-oneCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal