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Tegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalWhen converted and bioactivated to 5-FU, the drug mediates an anticancer activity by inhibiting thymidylate synthase (TS) during the pyrimidine pathway involved in DNA synthesis. 5-FU is listed on the … Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU by blocking the enzyme responsible for its degradation, or serves to limit the toxicity of 5-FU by
Mixtures: TS-ONE CAPSULE 20, TS-ONE CAPSULE 20International brands: ESUEEW AN TEzeprogind
go.drugbank.com/drugs/DB16954InvestigationalSynonyms: Azp-2006 free base, N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo(d)imidazol-2-amineOcriplasmin
go.drugbank.com/drugs/DB08888ApprovedWithdrawnFDA approved in October 17, 2012. … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system.
Naloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalIt was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.
Categories: Compounds used in a research, industrial, or household settingSynonyms: (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diolLonapegsomatropin
go.drugbank.com/drugs/DB16220ApprovedInvestigational, with growth failure due to insufficient growth hormone secretion. … [L36380,L10971] Lonapegsomatropin was granted FDA approval on 25 August 2021.[L36380] It was later approved by the European Commission on 13 January 2022.[L39900]
Plantago seed
go.drugbank.com/drugs/DB11097ApprovedInvestigationalIts potential benefit in maintaining remission in ulcerative colitis has been studied [A27156]. … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements.
Products: DG health Sugar Free, Fibrepur Pwr 100%Tildrakizumab
go.drugbank.com/drugs/DB14004ApprovedInvestigationalThe approved recommended dosage of ILUMYA is a subcutaneous injection of 100 mg at Weeks 0, 4, and every 12 weeks thereafter [L1858]. … A study was performed on the pharmacokinetics of this drug on various ethnicities. The pharmacokinetics of tildrakizumab were similar in Japanese, Caucasian, and Chinese subjects [A32257].
Lonafarnib
go.drugbank.com/drugs/DB06448ApprovedInvestigational[L23414, L23544] Lonafarnib was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies.[L23414, L23549] … Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature
Sodium bisulfite
go.drugbank.com/drugs/DB14015ApprovedWithdrawnSodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.
Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADET, HEPATAMINE %8 500 ML(SETLI)Categories: Compounds used in a research, industrial, or household settingHistrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawn[L41710] GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and the concentration of sex steroids. … As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by the FDA in May 2007).[L41700]
Synonyms: 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide