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Alfuzosin
go.drugbank.com/drugs/DB00346ApprovedThe prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. … [A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck.
Categories: Drugs Used in Benign Prostatic Hypertrophy, Cytochrome P-450 SubstratesSynonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamidePemlimogene merolisbac
go.drugbank.com/drugs/DB16286InvestigationalPemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab … Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Synonyms: (actan100), 5 tandem copies of a 21 amino acid fr, Recombinant live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids of the lm acta proteinIvabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalIvabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the … Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate
Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Mixtures: FluMisch 5% Minoxidil, Bakumokon 5% MinoxidilCategories: Heterocyclic Compounds, 1-Ring, Arteriolar Smooth Muscle, Agents Acting OnSinefungin
go.drugbank.com/drugs/DB01910ExperimentalSinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5S)-2,5-diamino-6-[(2R,3S,R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]hexanoic acid, 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-beta-D-ribo-decofuranuronic acidIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, 4-DemethoxydaunomycinAlbumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalAlso known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. … This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].
Products: Pulmocis 2 mg Kit für ein radioaktives Arzneimittel, NANOTOP 0,5 mg Kit für ein radioaktives ArzneimittelD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approvedL-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants.
Synonyms: D-Glucose in linear form, D-glucoseSalts: D-glucose monohydrateValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton.
Mixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in BeutelnCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such … It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Mixtures: Concor AM 5 mg/5 mg Tablets, CONCOR AMLO TABLET 5 mg/ 5 mgCategories: P-glycoprotein inhibitors, P-glycoprotein substrates