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Safinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalSafinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesAcrivastine
go.drugbank.com/drugs/DB09488ApprovedAcrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever.
Categories: Antihistamines for Systemic UseNitrogen
go.drugbank.com/drugs/DB09152ApprovedInvestigationalVet approvedLiquid nitrogen is used principally in cryotherapy for removal of diseased skin.
beta-Hydroxybutyric acid
go.drugbank.com/drugs/DB16506Investigational(completed for type 1 diabetes), and NCT05581043 (completed for type 2 diabetes). … Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236
Categories: Experimental Unapproved Treatments for COVID-19Prazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigationalPrazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefit...
Categories: Antihypertensive Agents Indicated for HypertensionDaxibotulinumtoxinA
go.drugbank.com/drugs/DB17929ApprovedInvestigational[L47865] On August 14, 2023, the drug was also approved for the treatment of cervical dystonia. … [L47870] DAXI or DAXXIFY, a product of daxibotulinumtoxinA, incorporates RTP004, a proprietary synthetic stabilizing peptide for enhanced product stability.[A261080, A261085]
Delandistrogene moxeparvovec
go.drugbank.com/drugs/DB16802ApprovedInvestigationalMicrodystrophin is a truncated, functional form of dystrophin. … Dystrophin is an essential protein responsible for muscle function; thus, patients with DMD experience a progressive deterioration of muscle mass and function.
Beroctocog alfa
go.drugbank.com/drugs/DB14473ApprovedInvestigationalMixtures: ALPHANATE FOR INJECTION 250 iu/vial, ALPHANATE FOR INJECTION 1000 iu/vialDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigational[L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia. … Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia.
Hyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigational[A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue.