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Displaying results 2331 - 2340 of 10000 in total
  1. Target

    Cytoplasmic tyrosine-protein kinase BMX

    go.drugbank.com/bio_entities/BE0009416
    TargetHumans

    Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival … May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells

    Synonyms: Epithelial and endothelial tyrosine kinase, Bone marrow tyrosine kinase gene in chromosome X protein
  2. Indication

    Multiple Endocrine Neoplasia

    go.drugbank.com/conditions/DBCOND0028176
    Drugs: Famotidine · Omeprazole
    Synonyms: Polyglandular activity in multiple endocrine adenomatosis, Polyglandular activity in multiple endocrine adenomatosis (disorder)
  3. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors.

    Categories: Ergot Alkaloids and Derivatives
  4. Indication

    Tenosynovitis

    go.drugbank.com/conditions/DBCOND0016032
    Drugs: Cortisone acetate · Dexamethasone
    Synonyms: Synovitis and tenosynovitis, Synovitis and tenosynovitis (disorder)
  5. Drug

    Nicorandil

    go.drugbank.com/drugs/DB09220
    ApprovedInvestigationalWithdrawn

    Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. … It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels.

    Categories: Vasodilators Used in Cardiac DiseasesSynonyms: N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate (ester)
  6. Indication

    Fungal infections of the cornea

    go.drugbank.com/conditions/DBCOND0104097
    Drugs: Natamycin
    Synonyms: Fungal infections in the cornea
  7. Drug

    Elbasvir

    go.drugbank.com/drugs/DB11574
    Approved

    Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). … Elbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly.

    Mixtures: ZEPATIER FILM-COATED TABLET 50MG/100MGCategories: elbasvir and grazoprevir
  8. Drug

    Dobesilic acid

    go.drugbank.com/drugs/DB13529
    Investigational

    Products: DOXIUM ® 500MG CAPSULAS, DOCALIX 500MG KAPSÜL ,30 KAPSÜL
  9. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    [A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992. This medication was later discontinued from the market in 1998.[L1113] … The obtained product is an antiviral ointment.[L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  10. Drug

    Lysine

    go.drugbank.com/drugs/DB00123
    ApprovedInvestigationalNutraceutical

    Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. … Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis.

    Mixtures: Aminosyn II and Dextrose, Aminosyn II and DextroseCategories: arginine and lysine, Blood and Blood Forming Organs