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Propyliodone
go.drugbank.com/drugs/DB09366ApprovedRadiopaque medium usually in oil; used in bronchography.
Categories: Compounds used in a research, industrial, or household settingMacitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.
Categories: Endothelin A Receptor AntagonistsMicrocrystalline cellulose
go.drugbank.com/drugs/DB14158ApprovedInvestigationalA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. … As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Categories: Compounds used in a research, industrial, or household settingNabilone
go.drugbank.com/drugs/DB00486ApprovedInvestigationalIf not provided in their activated form (such as through synthetic forms like Nabilone or [DB00470]), THC and CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A (THCA-A … From a pharmacological perspective, Cannabis' diverse receptor profile explains its potential application for such a wide variety of medical conditions.
Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approvedLotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. … [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.
Synonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamideTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigational[A229853, A229888, A229923, L32033] Following initial hydrolysis, further reactions liberate a highly reactive methyl diazonium cation capable of methylating various residues on adenosine and guanine bases … [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection.
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TEMODAL 140MG HKP IN BTL, TEMODAL 180MG HKP IN BTLRozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigational[A260192] As a result, the main clinical manifestation of myasthenia gravis is easily fatigable or persistent muscle weakness. … Rozanolixizumab is a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P) targeting the immunoglobulin G (IgG).
Emedastine
go.drugbank.com/drugs/DB01084ApprovedEmedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Polyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Categories: Compounds used in a research, industrial, or household settingProducts: ALCOHOL POLIVINILICO AL 1.4%, Cooper TearsGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigationalThis drug was approved after being designed as an orphan drug with a fast track and priority review status.[L4830] … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.