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TBI-223
go.drugbank.com/drugs/DB18911InvestigationalTBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Synonyms: CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, METHYL ESTERAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
Mixtures: Innoprax-5, ROSEL-TCategories: Influenza A M2 Protein Inhibitor, M2 Protein InhibitorsDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalFurthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties [A32377]. … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
Synonyms: D-panthenol 50, D-panthenolMixtures: XYLAZOL PEDİYATRİK 0,5 MG/ML + 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 10 ML, nasic - Nasenspray 10 mg/500 mgPrednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Synonyms: delta(1)-Hydrocortisone, delta(1)-DehydrocortisolInternational brands: Decortin H, Di-Adreson FTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalTheophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD. … Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Mixtures: THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADET, THEOLONG 1200/400 MG EFERVESAN TABLET, 10 ADETCategories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexIMT-288
go.drugbank.com/drugs/DB19068InvestigationalIMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
Synonyms: (4R)-5-(((1R)-1-CARBAMOYL-5-((2-((4-(2-(1H-IMIDAZOL-5-YL)ETHYLAMINO)-4-OXO-BUTANOYL)AMINO)ACETYL)AMINO)PENTYL)AMINO)-4-(((2R)-2-(((2R)-3-(4-HYDROXYPHENYL)-2-((2-(4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAZACYCLODODEC, -1-YL)ACETYL)AMINO)PROPANOYL)AMINO)-6-(Trimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ).
Mixtures: EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET, EMEDUR 200 MG SUPOZITUAR, 5 ADETSynonyms: N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamideIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.
Mixtures: ISOTREXIN JEL, 30 G, MUNDERM JEL , 30 GRAMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approvedPhenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications
Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexRupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalIt was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use. … Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: RUPAFIN® 10 MG, RUPATADINA EG