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Displaying results 2351 - 2360 of 10000 in total
  1. Target

    DNA damage-inducible transcript 4 protein

    go.drugbank.com/bio_entities/BE0003445
    TargetHumans

    Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes (By similarity). … Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage.

    Synonyms: Protein regulated in development and DNA damage response 1
  2. Drug

    Elbasvir

    go.drugbank.com/drugs/DB11574
    Approved

    Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). … Elbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly.

    Mixtures: ZEPATIER FILM-COATED TABLET 50MG/100MGCategories: elbasvir and grazoprevir
  3. Drug

    Omega-3-carboxylic acids

    go.drugbank.com/drugs/DB09568
    ApprovedWithdrawn

    The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. … [A25808] It was developed by AstraZeneca Pharmaceuticals and firstly approved by the FDA on May 05, 2014.[L2386]

    Mixtures: BiO-LiFE MaxX Fish Oil 1000mg Soft Capsule
  4. Indication

    Aphthous ulcer

    go.drugbank.com/conditions/DBCOND0010434
    Drugs: Chlorhexidine
    Synonyms: Foot-and-mouth disease, Foot and mouth disease
  5. Drug

    Lofexidine

    go.drugbank.com/drugs/DB04948
    ApprovedInvestigational

    [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018.[L2794] … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.

    Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders
  6. Drug

    Garadacimab

    go.drugbank.com/drugs/DB15629
    Approved

    [L53283,A273998] Garadacimab received its first approval in Australia and the UK in January 2025, and has since been approved in a number of other jurisdictions, including the EU and Japan. … [A273993] In June 2025, garadacimab was approved by the US FDA for the prophylaxis of HAE episodes in patients ≥12 years of age.

    Categories: Drugs Used in Hereditary Angioedema, Blood and Blood Forming Organs
  7. Drug

    Butropium

    go.drugbank.com/drugs/DB15968
    Experimental

    Products: COLIOPAN TABLET 5MG
  8. Drug

    Voxilaprevir

    go.drugbank.com/drugs/DB12026
    ApprovedInvestigational

    Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV) … with an HCV regimen containing sofosbuvir without an NS5A inhibitor [L935].

    Mixtures: VOSEVI FILM-COATED TABLETS 400MG/100MG/100MGCategories: Amino Acids, Peptides, and Proteins, sofosbuvir, velpatasvir and voxilaprevir
  9. Indication

    Laryngotracheitis

    go.drugbank.com/conditions/DBCOND0135807
    Drugs: Phenylephrine
    Synonyms: Acute laryngitis and tracheitis, Acute laryngitis and tracheitis (disorder)
  10. Indication

    Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

    go.drugbank.com/conditions/DBCOND0094035
    Drugs: Anakinra
    Synonyms: Chronic infantile neurological cutaneous and articular syndrome, CINCA - Chronic infantile neurological, cutaneous and articular syndrome