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Displaying results 2361 - 2370 of 7540 in total
  1. Target

    Steryl-sulfatase

    go.drugbank.com/bio_entities/BE0001197
    TargetEnzymeHumans

    Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid

    Synonyms: Estrone sulfatase
  2. Drug

    Etamivan

    go.drugbank.com/drugs/DB08989
    ApprovedWithdrawn

    Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.

  3. Drug

    Alectinib

    go.drugbank.com/drugs/DB11363
    ApprovedInvestigational

    Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed on or were not tolerant of crizotinib, which is associated with the development of resistance … It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC

  4. Drug

    Cetrimonium

    go.drugbank.com/drugs/DB01718
    ApprovedInvestigational

    Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.

    Synonyms: N,N,N-Trimethyl-1-hexadecanaminiumMixtures: QUIRUCIDAL NF, NW BENZALKONIUM AND CETRIMIDE CREAM
  5. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels. … The compound was proposed to bind to the reductase enzyme and was named compactin.

  6. Drug

    Pimavanserin

    go.drugbank.com/drugs/DB05316
    ApprovedInvestigational

    [A232783] It was approved by the FDA in April 2016 for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis thanks to favorable results from a pivotal six-week, randomized … [A232613,A232573] Pimavanserin is marketed under the trade name NUPLAZID and developed by Acadia Pharmaceuticals.

  7. Drug

    VidPrevtyn Beta

    go.drugbank.com/drugs/DB16427
    Approved

    VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from

  8. Drug

    Bromus secalinus pollen

    go.drugbank.com/drugs/DB10836
    Approved

    Bromus secalinus pollen is the pollen of the Bromus secalinus plant. Bromus secalinus pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic Extract
  9. Drug

    Elymus repens pollen

    go.drugbank.com/drugs/DB10489
    Approved

    Elymus repens pollen is the pollen of the Elymus repens plant. Elymus repens pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic Extract
  10. Drug

    Phalaris arundinacea pollen

    go.drugbank.com/drugs/DB10714
    Approved

    Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. Phalaris arundinacea pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic Extract