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Clomethiazole
go.drugbank.com/drugs/DB06470InvestigationalClomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesDeramciclane
go.drugbank.com/drugs/DB06512InvestigationalDeramciclane (EGIS-3886) is used for the treatment of a number of anxiety disorders. Deramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target. It antagonizes ...
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsLornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesBufuralol
go.drugbank.com/drugs/DB06726ExperimentalBufuralol is a new, non-selective -adrenoceptor blocking agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Synonyms: 3-(p-aminobenzenesulfonamido)-2-phenylpyrazoleCategories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C8 Inhibitors9-aminocamptothecin
go.drugbank.com/drugs/DB12515InvestigationalAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors3,5-diiodothyropropionic acid
go.drugbank.com/drugs/DB12629InvestigationalDITPA has been investigated in Congestive Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBalaglitazone
go.drugbank.com/drugs/DB12781InvestigationalBalaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitorsp-Quaterphenyl
go.drugbank.com/drugs/DB12794Investigationalp-Quaterphenyl has been used in trials studying the treatment of Malaria.