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Displaying results 2361 - 2370 of 10000 in total
  1. Drug

    Topiroxostat

    go.drugbank.com/drugs/DB01685
    Investigational

    While [DB00437] is considered a first-line therapy in treating hyperuricemic conditions, it is often associated with side effects and ineffective in reducing uric acid levels under recommended dosing regimens … Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.

    Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile
  2. Drug

    Bivatuzumab mertansine

    go.drugbank.com/drugs/DB33754
    Investigational

    Synonyms: Biwa-4 mertansine
  3. Drug

    Iniparib

    go.drugbank.com/drugs/DB13877
    Investigational

    Synonyms: 4-iodo-3-nitrobenzamide
  4. Drug

    Depulfavirine

    go.drugbank.com/drugs/DB18890
    Investigational

    Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

    Synonyms: 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
  5. Drug

    Sutetinib

    go.drugbank.com/drugs/DB18841
    Investigational

    Sutetinib is under investigation in clinical trial NCT05168566 (Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer).

    Synonyms: (2e)-n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-2-butenamide, 2-butenamide, n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-, (2e)-
  6. Drug

    Sutezolid

    go.drugbank.com/drugs/DB11905
    Investigational

    Sutezolid has been used in trials studying the treatment of Tuberculosis.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: ACETAMIDE, N-((3-(3-FLUORO-4-(4-THIOMORPHOLINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, (S)-, N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
  7. Drug

    Aminoflavone

    go.drugbank.com/drugs/DB19077
    Investigational

    Aminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 4h-1-benzopyran-4-one, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4h-1-benzopyran-4-one
  8. Drug

    N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine

    go.drugbank.com/drugs/DB03013
    Experimental

    Synonyms: N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine, β-D-GlcNAc-(1→4)-β-D-GlcNAc
  9. Drug

    GSK-269962A

    go.drugbank.com/drugs/DB17030
    Experimental

    GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.[A253012]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzamide, n-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl)ethoxy)-, N-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl)ethoxy)benzamide
  10. Drug

    Avoralstat

    go.drugbank.com/drugs/DB12120
    Investigational

    Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acid