Search
Inner membrane complex sub-compartment protein 3
go.drugbank.com/bio_entities/BE0009269TargetPlasmodium falciparum (isolate 3D7)Polypeptides: Inner membrane complex sub-compartment protein 3Birch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational[L42380] Two oleogel formulations of birch bark extract (Oleogel-S10, 10% of triterpene dry extract in sunflower oil) have been approved by the European Medicines Agency. … [L42365,L42370] Filsuvez, one of these two formulations, is approved for the treatment of partial thickness wounds in patients with epidermolysis bullosa (EB), a rare group of hereditary disorders of the
Categories: Complex MixturesUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A244210] Ublituximab is a chimeric anti-CD20 IgG1κ antibody produced in the rat YB2/0 cell line to target a unique epitope and enhance ADCC compared to other approved anti-CD20 antibodies such as [rituximab … [A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG Therapeutics in 2012.
Streptococcus pneumoniae type 14 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10332ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: SYNFLORIX 0,5 ML IM ENJ. ICIN SUS.ICEREN KUL.HAZIR ENJEKTOR, Prevnar 20Pranoprofen
go.drugbank.com/drugs/DB13514InvestigationalPranoprofen is an anti-inflammatory agent.
Products: OFTALAR STERIL GOZ DAMLASI 5 MLCelivarone
go.drugbank.com/drugs/DB16012InvestigationalCelivarone is under investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 Mg OD With Amiodarone as … Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/flutter).
Levomilnacipran
go.drugbank.com/drugs/DB08918ApprovedInvestigational[L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for stroke in Europe, the EMA decided against this use.[L48011] … [L47946] First approved by the FDA on July 25, 2013, levomilnacipran is used to treat major depressive disorder in adults.
Synonyms: CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)-Quizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigational[A260641] Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although with a 10-fold lower affinity compared to wild-type FLT3. … with other targets in mind.
Synonyms: N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)ureaAxicabtagene ciloleucel
go.drugbank.com/drugs/DB13915ApprovedInvestigationalAxicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … [A216163] Axicabtagene ciloleucel was approved by the FDA on October 18th, 2017.
Categories: Complex MixturesSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptorHolliday junction branch migration complex subunit RuvB
go.drugbank.com/bio_entities/BE0001514TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication … The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.
Polypeptides: Holliday junction branch migration complex subunit RuvB