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Strontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedThere has been some cases of apparent tumor regression which has given it a potential tumoricidal effect.[A31263]
Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalIts potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated.
Avutometinib
go.drugbank.com/drugs/DB15254ApprovedInvestigational[L53203] It has been under investigation in humans since at least 2012.
Nonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnN-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Ferric maltol
go.drugbank.com/drugs/DB15598ApprovedInvestigational[A189288] Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency.
2-Methoxyestradiol
go.drugbank.com/drugs/DB02342Investigational2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2...
Repaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Protein S100-P
go.drugbank.com/bio_entities/BE0001191TargetHumansMay function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like ...
Synonyms: Migration-inducing gene 9 proteinN,N,N-trimethylglycinium
go.drugbank.com/drugs/DB04455InvestigationalA naturally occurring compound that has been of interest for its role in osmoregulation. … As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria.
Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalTazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a vari...