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Terazosin
go.drugbank.com/drugs/DB01162ApprovedInvestigationalTerazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837]. … Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831].
Mixtures: Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg, Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mgCategories: Genito Urinary System and Sex HormonesCarthamus tinctorius flower bud
go.drugbank.com/drugs/DB14278ApprovedCarthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Safflower Flower Bud, Calcitrapa Tinctoria Flower BudCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Ng Citalopram, Nu-citalopramFazpilodemab
go.drugbank.com/drugs/DB18924InvestigationalFazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis
Synonyms: Bfkb-8488a (bispecific antibody designed to mimic the metabolic hormone fgf21)., immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chainBazlitoran
go.drugbank.com/drugs/DB14990InvestigationalBazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Synonyms: Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9, -(3'->5')-2'-O-METHYL-P-THIOURIDYLYL-(Categories: Nucleic Acids, Nucleotides, and NucleosidesAluminum sulfate
go.drugbank.com/drugs/DB11239ApprovedBy overcoming the body barriers, Al may infiltrate into the blood and lead to toxic effects in liver, bone and the central nervous system [L2145]. … Al is found in materials used in the pharmaceutical industry, and in manufactured foodstuffs, cosmetics, and tap water.
Products: Rastringent II 250mg/ml, Sil Trax As No 8Chlorpromazine
go.drugbank.com/drugs/DB00477ApprovedInvestigationalVet approvedLike the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Synonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.
Mixtures: Foster and Thrive Allergy and Congestion D, Allergy and CongestionCategories: Histamine H1 Antagonists, Non-SedatingRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalIt was originally approved by the U.S. … The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences [A40017], [FDA label].
Categories: Amino Acids, Peptides, and Proteins, Monoclonal antibodies and antibody drug conjugatesProducts: RITOXEN 10MG/ML, IXIMAB® 10MG/MLDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnA synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. … (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Categories: Estrogens, Non-Steroidal, Hormones and Related AgentsProducts: Honvol Ampoules 250mg, Honvol Tablets 100mg