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Sugammadex
go.drugbank.com/drugs/DB06206ApprovedInvestigationalSugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery. … Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015.
Products: BRIDION 500 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN 10 FLAKON, SUGRİNO 500 MG/5 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADETAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA gr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: YULAREB 100 MG FİLM KAPLI TABLET, 56 ADET, VERZENIO® 100 MGIzokibep
go.drugbank.com/drugs/DB19081InvestigationalIzokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).
Synonyms: TO TWO HOMODIMER SUBUNITS OF HUMAN INTERLEUKIN 17A (, FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDINGOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[A246015] Olaparib is used to treat a number of BRCA-associated tumours, including ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. … [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820]
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A InducersProducts: LYNPARZA 100 MG FİLM KAPLI TABLET, 56 TABLET, LYNPARZA® 100 MGUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalFrom its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.
Mixtures: Medi-10, PreQue 10Synonyms: Co-enzyme Q 10, Coenzyme Q 10Procaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedA local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: NTCAIN 100 MG/10 ML IM AMPUL, 50 ADET, NTCAIN 50 MG/5 ML IM AMPUL , 100 ADETValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalValproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. … In 1963, a serendipitous discovery was made by George Carraz during his investigations into the anticonvulsant effects of khelline when he found that all of his samples, dissolved in valproic acid, exerted
Mixtures: PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADET, PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADETCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalOther drug products with similar structure and function to Antihemophilic factor human include [DB13999], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced … Factor VIII, but does not contain the B-domain, which has no known biological function and [DB11607], which is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared
Mixtures: BIOSTATE FOR INJECTION 50 iu/ml, IMMUNATE 1000 IU/750 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADETProducts: HAEMOCTİN SDH 500 IU/10 ML IV ENJEKSİYONLUK TOZ VE ÇÖZÜCÜ, EMOCLOT 500 IU/10 ML IV INFUZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADETPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalThe mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT1 Receptor AntagonistsProducts: @ctavis 100 mg Depot-Injektionssuspension, @ctavis 150 mg Depot-InjektionssuspensionPapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
International brands: Ro-PapavProducts: PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 100 ADET, PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 10 ADET