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Displaying results 231 - 240 of 10000 in total
  1. Drug

    Imlunestrant

    go.drugbank.com/drugs/DB19043
    ApprovedInvestigational

    The FDA approved imlunestrant on September 25, 2025 [L54051] as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer with … Imlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader.

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: (5r)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5r)-
  2. Drug

    Scarlet red

    go.drugbank.com/drugs/DB19136
    ApprovedWithdrawn

    Scarlet red is under investigation in clinical trial NCT00591916 (New Treatment for Donor Sites).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 2',3-dimethyl-4-(2-hydroxynaphthylazo) azobenzene, 1-((2-methyl-4-((2-methylphenyl)azo)phenyl)azo)-2-naphthalenol
  3. Drug

    Thiabendazole

    go.drugbank.com/drugs/DB00730
    ApprovedVet approvedWithdrawn

    2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 2-(thiazol-4-yl)benzimidazole, 4-(2-benzimidazolyl)thiazole
  4. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    It is a component of cough and cold medicines. It may cause drowsiness.

    Mixtures: ACTİFED 30 MG/5 ML + 1,25 MG/5 ML ŞURUP, PEACEF SYRUP 30 mg/5 mlCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL

    go.drugbank.com/drugs/DB08611
    Experimental

    Synonyms: 2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL
  6. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine
  7. Drug

    Balsalazide

    go.drugbank.com/drugs/DB01014
    Approved

    The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. … Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA.

    Categories: Non COX-2 selective NSAIDSSynonyms: 3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid, (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid
  8. Drug

    Stavudine

    go.drugbank.com/drugs/DB00649
    ApprovedInvestigational

    A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

    Mixtures: TRIVIRO LNS® LAMIVUDINA 150 MG NEVIRAPINA 200 MG ESTAVUDINA 40 MG, TRESLAM ® 30Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Islatravir

    go.drugbank.com/drugs/DB15653
    ApprovedInvestigational

    [A275492] On April 21, 2026, the FDA approved the first fixed-dose combination containing islatravir (0.25 mg) and the NNRTI doravirine (100 mg), marketed as IDVYNSO, as a complete once-daily regimen for … [A275492, L56138] Chemically, it is a deoxyadenosine analogue distinguished by a 4'-ethynyl group and a 2-fluoro substitution, which collectively enhance its metabolic stability and potency.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 4'-ethynyl-2-fluoro-2'-deoxyadenosine
  10. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.

    Mixtures: InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung, OTOFAST®Categories: 4-Quinolones, MATE 2 Inhibitors