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Taletrectinib
go.drugbank.com/drugs/DB18711ApprovedInvestigational[L53308] Gene fusions involving _ROS1_, a proto-oncogene, have been identified as oncogenic drivers in 1-2% of patients with non-small cell lung cancer (NSCLC), in addition to other cancers at variable … [A274118] Taletrectinib was approved by the US FDA in June 2025 for use in patients with advanced ROS1-positive NSCLC.[L53308,L53523]
Pentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnWhen administered, pentastarch remains mainly in the circulatory system and hence, it is considered a plasma expander. … It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation.
Categories: Compounds used in a research, industrial, or household settingImgatuzumab
go.drugbank.com/drugs/DB14884InvestigationalImgatuzumab is under investigation in clinical trial NCT01326000 (A Study of RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With
Idarucizumab
go.drugbank.com/drugs/DB09264Approved, concomitant NSAID or warfarin use, etc). … Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its
Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/MLPrezatide
go.drugbank.com/drugs/DB11296ApprovedIt is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer are currently being investigated. … Prezatide is used in cosmetic products for the skin and hair.
Human cytomegalovirus immune globulin
go.drugbank.com/drugs/DB13886ApprovedInvestigationalAs a consequence, CMV disease is restricted to the immunocompromised or immunologically immature host, in which it can lead the devastating result of transplant rejection [A32498], [L2229]. … It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].
Insulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50763] It has also been approved in Japan and Australia. … It is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life.
Categories: Drugs Used in DiabetesAcetazolamide
go.drugbank.com/drugs/DB00819ApprovedInvestigationalVet approvedIt is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual … Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition
Synonyms: N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide, N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamideProducts: ACETAZOLAMIDA 250 MG, Diamox 250 mg - TablettenInavolisib
go.drugbank.com/drugs/DB15275ApprovedInvestigational[L51748,L51738] In February 2025, it was approved by Health Canada for the same indication. [L52605] … _PIK3CA_ is one of the most frequently mutated oncogenes, with the resulting mutated p110α protein it encodes playing a central role in tumor cell proliferation.
Acarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalIt inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex … Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines.
Categories: Drugs Used in DiabetesProducts: ACARBOSA 50 MG, ACARBOSA 100 MG