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Displaying results 2401 - 2410 of 2828 in total
  1. Drug

    ECT-001 expanded cord blood

    go.drugbank.com/drugs/DB21745
    Investigational

    [L52013] It is being investigated in hematopoietic cell transplantation as ECT-001 expanded cord blood can demonstrate enhanced stem cell proliferation and engraftment compared to untreated UBCs.

  2. Drug

    Gamcemetinib

    go.drugbank.com/drugs/DB21624
    Investigational

    The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor.

  3. Target

    Serine/threonine-protein kinase mTOR

    go.drugbank.com/bio_entities/BE0002386
    TargetHumans

    Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1 (PubMed:32561715). … The mTORC2 complex also phosphorylates various proteins involved in insulin signaling, such as FBXW8 and IGF2BP1 (By similarity).

    Synonyms: FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1
  4. Drug

    Aprindine

    go.drugbank.com/drugs/DB01429
    Experimental

    Aprindine is a cardiac depressant used in arrhythmias.

    Categories: Membrane Transport Modulators
  5. Drug

    Methylenedioxyethamphetamine

    go.drugbank.com/drugs/DB01566
    ExperimentalIllicit

    Categories: Membrane Transport Modulators
  6. Drug

    Pipendoxifene

    go.drugbank.com/drugs/DB05414
    Investigational

    Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an excellent preclinical pharmacological profile and was selected for further development as a treatment

  7. Target

    Proteasome subunit beta type-2

    go.drugbank.com/bio_entities/BE0002349
    TargetHumans

    Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C7-I
  8. Drug

    Protiofate

    go.drugbank.com/drugs/DB13632
    Experimental

    Categories: Genito Urinary System and Sex Hormones
  9. Drug

    Gestonorone

    go.drugbank.com/drugs/DB13230
    Experimental

    Gestonorone is often mistaken for gestonorone capproate which has a different chemical structure.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  10. Drug

    Cyclo(his-pro)

    go.drugbank.com/drugs/DB02414
    Experimental

    Categories: Membrane Transport Modulators