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go.drugbank.com/drugs/DB17297InvestigationalSynonyms: 2-pyridinamine, 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-(4-(((s(s))-s-methylsulfonimidoyl)methyl)-2-pyridinyl)-Paxalisib
go.drugbank.com/drugs/DB15186InvestigationalGDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Synonyms: 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amineCategories: Heterocyclic Compounds, 1-RingFexagratinib
go.drugbank.com/drugs/DB12247InvestigationalAZD4547 has been used in trials studying the treatment of Cancer, LYMPHOMA, Gastric Cancer, Adenocarcinoma, and Solid Neoplasm, among others.
Synonyms: N-(5-(2-(3,5-DIMETHOXYPHENYL)ETHYL)-1H-PYRAZOL-3-YL)-4-((3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL)BENZAMIDEHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Synonyms: Reichstein's substance M, 4-pregnen-11β,17α,21-triol-3,20-dioneInternational brands: Polcort H, Preparation H Hydrocortisone CreamLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalIt was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805] … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML, VITRAKVI 25 MG SERT KAPSÜL, 56 ADETTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.
Synonyms: poly(styrene-4-sulfonic acid)International brands: Resonium APheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs.
Mixtures: ANTIBEKSIN SURUP, 100 ML, Rhume Et De LA Grippe (extra-fort)Categories: Heterocyclic Compounds, 1-Ring, Antihistamines, Anesthetics, Etc.Dydrogesterone
go.drugbank.com/drugs/DB00378ApprovedInvestigationalWithdrawnA synthetic progestational hormone with no androgenic or estrogenic properties.
Mixtures: Femoston conti 1 mg/5 mg Filmtabletten, Femoston 2/10 TabletCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCarglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalFood and Drug Administration (FDA) on 18 March 2010. … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase.
Synonyms: (2S)-2-(carbamoylamino)pentanedioic acid, (S)-2-ureidopentanedioic acidCategories: Carbamoyl Phosphate Synthetase 1 Activator, Carbamoyl Phosphate Synthetase 1 ActivatorsN-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
go.drugbank.com/drugs/DB04057ExperimentalSynonyms: N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid, β-DADF, MSA, multisubstrate adduct inhibitor