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Displaying results 2401 - 2410 of 8696 in total
  1. Target

    T cell receptor delta variable 2

    go.drugbank.com/bio_entities/BE0023749
    TargetHumans

    V region of the variable domain of T cell receptor (TR) delta chain that participates in the antigen recognition (PubMed:24600447).

    Polypeptides: T cell receptor delta variable 2
  2. Drug

    Sofosbuvir

    go.drugbank.com/drugs/DB08934
    ApprovedInvestigational

    NS5B, an RNA-dependent RNA polymerase, is essential for the transcription of Hepatitis C viral RNA and for its high replicative rate and genetic diversity [A19594]. … This is an important advantage relative to HCV drugs that target other viral enzymes such as the protease, for which rapid development of resistance has proven to be an important cause of therapeutic failure

    Categories: P-glycoprotein substrates, Antivirals for Systemic Use
  3. Drug

    Mipomersen

    go.drugbank.com/drugs/DB05528
    Approved

    Mipomersen is indicated in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications.

    Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia
  4. Drug

    Macimorelin

    go.drugbank.com/drugs/DB13074
    Approved

    In addition, individuals with may be susceptible to cardiovascular complications from altered structures and function [A31484]. … More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH secretagogue receptor, or ghrelin receptor (GHS-R1a) to dose-dependently increase GH levels

    Categories: Tests for Pituitary Function, Cytochrome P-450 Substrates
  5. Drug

    Procaine benzylpenicillin

    go.drugbank.com/drugs/DB09320
    ApprovedVet approved

    Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections. … Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic.

    Mixtures: Bicillin A-P Injection PwsCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  6. Drug

    AP5346

    go.drugbank.com/drugs/DB04992
    Investigational

    AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer.

  7. Drug

    Secnidazole

    go.drugbank.com/drugs/DB12834
    ApprovedInvestigational

    [A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and Africa for decades. … Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: SECNIDAZOL 500 MG POLVO P RECONSTRUIR, SECNIDAZOL 750 MG POLVO P. RECOSTRUIR
  8. Drug

    Lucanthone

    go.drugbank.com/drugs/DB04967
    Investigational

    One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.

  9. Drug

    Measles virus vaccine live attenuated

    go.drugbank.com/drugs/DB10315
    ApprovedInvestigational

    Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease.

    Mixtures: Sterile Diluent for M-M-R II, <p>SII MEASLES,MUMPS &amp; RUBELLA VACCINE LIVE ATTENUATED (FREEZE-DRIED) SINGLE DOSE</p>
  10. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.

    Mixtures: Zuades 5 mg/1,25 mg Tabletten zur Herstellung einer Suspension zum Einnehmen für ein Dosiergerät, Duodopa, 20 mg/ml + 5 mg/ml, Gel zur intestinalen Anwendung