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2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE
go.drugbank.com/drugs/DB07605ExperimentalSynonyms: 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDEN-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE
go.drugbank.com/drugs/DB07790ExperimentalSynonyms: N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDELarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalIt was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805] … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML, VITRAKVI 25 MG SERT KAPSÜL, 56 ADETPheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs.
Mixtures: ANTIBEKSIN SURUP, 100 ML, Rhume Et De LA Grippe (extra-fort)Categories: Heterocyclic Compounds, 1-Ring, Antihistamines, Anesthetics, Etc.Hydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Synonyms: Reichstein's substance M, 4-pregnen-11β,17α,21-triol-3,20-dioneInternational brands: Polcort H, Preparation H Hydrocortisone CreamDydrogesterone
go.drugbank.com/drugs/DB00378ApprovedInvestigationalWithdrawnA synthetic progestational hormone with no androgenic or estrogenic properties.
Mixtures: Femoston conti 1 mg/5 mg Filmtabletten, Femoston 2/10 TabletCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.
Synonyms: poly(styrene-4-sulfonic acid)International brands: Resonium ACarglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalFood and Drug Administration (FDA) on 18 March 2010. … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase.
Synonyms: (2S)-2-(carbamoylamino)pentanedioic acid, (S)-2-ureidopentanedioic acidCategories: Carbamoyl Phosphate Synthetase 1 Activator, Carbamoyl Phosphate Synthetase 1 ActivatorsN-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
go.drugbank.com/drugs/DB04057ExperimentalSynonyms: N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid, β-DADF, MSA, multisubstrate adduct inhibitorExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. … Exenatide was given FDA approval on April 28, 2005[L6106]. It is available as immediate- and extended-release formulations.
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsSynonyms: Exendin 4, Exendin-4