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Displaying results 2411 - 2420 of 10000 in total
  1. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    As a result, inhibition of ADP-mediated platelet activation and aggregation occurs. … Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: PERKUNAL 5, PRASUGREL BETA 5 MG FTA
  2. Target

    Vitamin D-binding protein

    go.drugbank.com/bio_entities/BE0001141
    CarrierTargetHumans

    Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation

    Synonyms: DBP-maf, Gc-MAF
  3. Drug

    Zamubafusp alfa

    go.drugbank.com/drugs/DB32269
    Investigational

    Zamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]

  4. Drug

    GI-5005

    go.drugbank.com/drugs/DB05942
    Investigational

    Tarmogens are believed to activate both an innate immune response via Toll-like receptors (TLRs), as well as an adaptive, antigen specific cellular immune response. … GI-5005 is GlobeImmune's lead infectious disease product from its proprietary Tarmogen active immunotherapy platform for the treatment of chronic hepatitis C infection.

  5. Drug

    Cosibelimab

    go.drugbank.com/drugs/DB15770
    ApprovedInvestigational

    Cosibelimab is a human IgG1 lambda monoclonal antibody directed against programmed death ligand-1 (PD-L1).

    Categories: Programmed Death Ligand-1 Blocker, Programmed Death Receptor-1 Blocking AntibodySynonyms: IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1, CD274 ANTIGEN))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV1-69*01 (94%) (IGHD)-IGHJ1, *01) (8.8.13) (1-120)-HOMO SAPIENS IGHG1*01 (121-45
  6. Drug

    Polythiazide

    go.drugbank.com/drugs/DB01324
    Approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)

    Mixtures: Renese-RCategories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Bromfenac

    go.drugbank.com/drugs/DB00963
    ApprovedWithdrawn

    Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. … Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation.

    Categories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Synonyms: [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid, 2-amino-3-(4-bromobenzoyl)benzeneacetic acid
  8. Drug

    Lenograstim

    go.drugbank.com/drugs/DB13144
    ApprovedWithdrawn

    Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.

    Synonyms: G-CSF (CHO cell derived), Glycosylated recombinant G-CSFProducts: GRANOCYTE 34 MU ENJEKSİYONLUK/İNFÜZYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET
  9. Drug

    Eslicarbazepine

    go.drugbank.com/drugs/DB14575
    Approved

    Eslicarbazepine is an anti-epileptic medication available commercially as [eslicarbazepine acetate].

    Categories: Cytochrome P-450 CYP3A Inducers, Heterocyclic Compounds, 3-RingSynonyms: S(+)-Liscarbazepine
  10. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination. … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.

    Categories: OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUM, L-OHP