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Influenza A virus A/Hong Kong/2671/2019 (H3N2) live (attenuated) antigen
go.drugbank.com/drugs/DB15757ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Synonyms: Influenza A virus A/Hong Kong/2671/2019 (H3N2) live (attenuated) antigenAsparaginase Erwinia chrysanthemi
go.drugbank.com/drugs/DB08886ApprovedInvestigational[L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of L-asparaginase, including [Asparaginase Escherichia coli] and a pegylated form of this enzyme, [Pegaspargase … [A236344] Studies show that substitution of _Erwinia_ asparaginase for _E. coli_-derived asparaginase following an allergic reaction has been safe and effective.
Synonyms: Erwinia L-asparaginase, L-asparaginase (Erwinia)Proline dehydrogenase 1, mitochondrial
go.drugbank.com/bio_entities/BE0002330TargetEnzymeHumansConverts proline to delta-1-pyrroline-5-carboxylate
Synonyms: p53-induced gene 6 proteinMolybdenum cofactor biosynthesis protein 1
go.drugbank.com/bio_entities/BE0011005TargetHumansIsoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP) (PubMed:11891227, PubMed:23627491, PubMed:29368224, PubMed:31996372). MOCS1A catalyzes the cycl...
Synonyms: Cell migration-inducing gene 11 proteinHypoxia-inducible factor 1
go.drugbank.com/bio_entities/BE0010297TargetHumansgene promoters (PubMed:28396409, PubMed:34521881). … Forms heterodimers with the aryl hydrocarbon receptor (AHR) to mediate the transcriptional response to xenobiotics by binding xenobiotic response elements (XREs) or dioxin response elements (DREs) in target
Polypeptides: Aryl hydrocarbon receptor nuclear translocatorSynonyms: Dioxin receptor, nuclear translocatorIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalResistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 InducersXEN-D0101
go.drugbank.com/drugs/DB06020ExperimentalXEN-D0101 works by being a selective antagonist of the voltage-gated potassium channel Kv1.5.
Categories: Heterocyclic Compounds, 1-RingFerritin
go.drugbank.com/bio_entities/BE0010292CarrierHumansDelivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223) … Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293)
Synonyms: Cell proliferation-inducing gene 15 proteinDextrose, unspecified form
go.drugbank.com/drugs/DB09341ApprovedInvestigationalVet approvedL-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants.
Mixtures: D-5-1/3 S, D-5-SCategories: Compounds used in a research, industrial, or household settingAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalallergic rhinitis in patients 6 years of age and older. … [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal
Mixtures: N-S-4, ALERXY® CCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates