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Displaying results 2451 - 2460 of 3889 in total
  1. Drug

    Pamiparib

    go.drugbank.com/drugs/DB14769
    Investigational

    Pamiparib is under investigation in clinical trial NCT03933761 (Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose P...

    Categories: Poly (ADP-ribose) polymerase (PARP) inhibitors
  2. Drug

    Olaptesed Pegol

    go.drugbank.com/drugs/DB11707
    Investigational

    Olaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation.

  3. Drug

    ASP-7317

    go.drugbank.com/drugs/DB18549
    Investigational

    ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.

  4. Drug

    AEM-28-14

    go.drugbank.com/drugs/DB17643
    Experimental

    AEM-28-14 is an analog of [AEM-28], an apolipoprotein E mimetic peptide, with a 400 percent greater cholesterol-lowering efficacy and a several-fold increase in drug tolerability.

  5. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used...

  6. Target

    IgG heavy chain

    go.drugbank.com/bio_entities/BE0010027
    TargetCarrier

    Ig gamma-4 (IgG4) isotype does not elicit antibody-dependent cellular cytotoxicity (ADDC) or complement-dependent cytotoxicity (CDC). … Instead it is likely involved in immune tolerance mechanisms to allergens and parasites either by blocking IgE-antigen complex formation or by directly inhibiting mast cell degranulation through Fc receptor

    Synonyms: Ig gamma-1 chain C region EU, Ig gamma-2 chain C region DOT
  7. Drug

    Renadirsen

    go.drugbank.com/drugs/DB19132
    Investigational

    Renadirsen is under investigation in clinical trial NCT04433234 (Long-term, Extension Study of Ds-5141b in Patients With Duchenne Muscular Dystrophy).

  8. Drug

    GT 389-255

    go.drugbank.com/drugs/DB05894
    Experimental

    Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and

  9. Drug

    Gestrinone

    go.drugbank.com/drugs/DB11619
    Approved

    Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatmen...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  10. Drug

    Norethynodrel

    go.drugbank.com/drugs/DB09371
    Approved

    A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combin...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System