Search

Displaying results 2451 - 2460 of 10000 in total
  1. Drug

    Serplulimab

    go.drugbank.com/drugs/DB17451
    ApprovedInvestigational

    Serplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa.
  2. Drug

    (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone

    go.drugbank.com/drugs/DB04135
    Experimental

    Synonyms: (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone, (4S)-5-Fluoro-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one
  3. Drug

    Eltrapuldencel-T

    go.drugbank.com/drugs/DB17329
    Investigational

    Synonyms: Autologous dendritic cells loaded with antigen from self-renewing, proliferating autologous irradiated tumour cells, in a solution of granulocyte-macrophage colony stimulating factor (GM-CSF), Eltrapuldencel-T
  4. Drug

    Erteberel

    go.drugbank.com/drugs/DB07933
    Investigational

    Erteberel is an estrogen receptor beta agonist that has been used in trials studying the treatment of Benign Prostatic Hyperplasia.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (3aS,4R,9bR)-4-(4-Hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta(c)(1) benzopyran-8-ol
  5. Drug

    Myricetin

    go.drugbank.com/drugs/DB02375
    Experimental

    Synonyms: 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one, 3,3',4',5,5',7-HexahydroxyflavoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Zinc dibutyldithiocarbamate

    go.drugbank.com/drugs/DB14194
    Approved

    Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.

    Synonyms: (T-4)-bis(dibutylcarbamodithioato-κS,κS')zinc
  7. Drug

    ADL-5859

    go.drugbank.com/drugs/DB18910
    Investigational

    ADL-5859 is under investigation in clinical trial NCT00626275 (Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: BENZAMIDE, N,N-DIETHYL-4-(5-HYDROXYSPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDIN)-4-YL)-
  8. Drug

    Tolmetin

    go.drugbank.com/drugs/DB00500
    Approved

    A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid, 1-Methyl-5-p-toluoylpyrrole-2-acetic acid
  9. Drug

    Nutlin-3

    go.drugbank.com/drugs/DB17039
    Experimental

    Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.[A253057]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-piperazinone, 4-(((4r,5s)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1h-imidazol-1-yl)carbonyl)-, rel-, Nutlin-3
  10. Drug

    TSN-084

    go.drugbank.com/drugs/DB18306
    Investigational

    Synonyms: 3-PYRIDINECARBOXAMIDE, N-(3-FLUORO-4-((1-METHYL-6-(1H-PYRAZOL-4-YL)-1H-INDAZOL-5-YL)OXY)PHENYL)-1-(4-FLUOROPHENYL)-1,2-DIHYDRO-6-(1-METHYLETHOXY)-2-OXO-, N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-(1-methylethoxy)-2-oxo-3-pyridinecarboxamide