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Dapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigational[A261601] Dapagliflozin was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2 diabetes in conjunction with diet and exercise. … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2.
Mixtures: XIGDUO XR (TABLETS 5 MG/1000 MG), Qtern 5 mg/10 mg Film-Coated TabletsCategories: Drugs Used in Diabetes, P-glycoprotein substratesCendakimab
go.drugbank.com/drugs/DB18427InvestigationalCendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Synonyms: )) (10.7.15) (1-123) -HOMO SAPIENS IGHG1*03V, G1M3>G, IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL-13 (INTERLEUKIN 13, IL-13)), HUMANIZED MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN HUMANIZED (1-453) (VH (HOMO SAPIENS IGHV2-5*08 (80.6%) -(IGHD) -IGHJ4*01 (100%Polidocanol
go.drugbank.com/drugs/DB06811ApprovedInvestigationalPolidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower … The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and a mean molecular weight of approximately 600.
Mixtures: KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADET, SOLCOSERYL ADHEZIV DIS PATI, 5 GCategories: Compounds used in a research, industrial, or household settingTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.
Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-ACarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigationalIndividuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. … reported by physicians in France and Italy.
Mixtures: TUSSYL® MIEL JARABE, AXIM TOSTHERAPY FORTE®Synonyms: (L)-2-Amino-3-(carboxymethylthio)propionic acid, (R)-S-(carboxymethyl)cysteinePotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release
Mixtures: CLORURO DE POTASIO 20 MEQ/L. CLORURO DE SODIO 40 MEQ/L EN DEXTROSA AL 5% X 250 ML, CLORURO DE POTASIO 20 MEQ/L. CLORURO DE SODIO 40 MEQ/L. EN DEXTROSA 5%International brands: Slow-K, Micro-KFluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalFluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. … It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].
Mixtures: FLUCONAZOL+SECNIDAZOL 75MG/1000 MG, FLUCONAZOL+SECNIDAZOL 75MG/1000 MGCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[L41820] Later, it was approved under a different brand name ZEPBOUND on November 8, 2023, for the chronic weight management in adults with obesity or overweight with at least one weight-related condition … [L48766] On September 15, 2022, tirzepatide was also approved by the European Commission.[L44386]. On November 02, 2023, tirzepatide was also approved by the Health Canada [L52800]
Categories: Receptors, G-Protein-Coupled, Drugs Used in DiabetesProducts: Mounjaro 5 mg solution for injection in pre-filled pen, Mounjaro 5 mg solution for injection in vialNitisinone
go.drugbank.com/drugs/DB00348ApprovedNitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedioneFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A1 SubstratesProducts: FLUVASTATINA EG, Fluvastatin Sodium ER