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Displaying results 2461 - 2470 of 10000 in total
  1. Drug

    Cerlapirdine

    go.drugbank.com/drugs/DB12229
    Investigational

    Cerlapirdine has been investigated for the treatment of Alzheimer Disease.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Ferric maltol

    go.drugbank.com/drugs/DB15598
    ApprovedInvestigational

    [A189288] Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency. … Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Nonoxynol-9

    go.drugbank.com/drugs/DB06804
    ApprovedWithdrawn

    N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. … Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Nonoxynol 9, Nonoxynol-9
  4. Drug

    Strontium chloride Sr-89

    go.drugbank.com/drugs/DB09498
    Approved

    There has been some cases of apparent tumor regression which has given it a potential tumoricidal effect.[A31263] … [A31264] Bone metastases is a common and severe complication presented in advanced stages of the disease.

  5. Drug

    Clofarabine

    go.drugbank.com/drugs/DB00631
    ApprovedInvestigational

    Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated. … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand.

    Categories: Heterocyclic Compounds, 2-Ring, OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
  6. Drug

    Avutometinib

    go.drugbank.com/drugs/DB15254
    ApprovedInvestigational

    [L53203] It has been under investigation in humans since at least 2012. … Avutometinib is a small molecule kinase inhibitor targeted against RAF/MEK1, key regulators of the RAS/RAF/MEK/ERK (MAPK) pathway.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: N-(3-fluoro-4-((4-methyl-2-oxo-7-((pyrimidin-2-yl)oxy)-2H-1-benzopyran-3-yl)methyl)pyridin-2-yl)-N'-methylsulfuric diamide, Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl)-N'-methyl-
  7. Drug

    Navarixin

    go.drugbank.com/drugs/DB11711
    Investigational

    Navarixin has been investigated for the treatment of Asthma.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    AN-2718

    go.drugbank.com/drugs/DB12810
    Investigational

    An2718 has been used in trials studying Tinea Pedis.

  9. Drug

    Irdabisant

    go.drugbank.com/drugs/DB12900
    Investigational

    Irdabisant has been used in trials studying Cognitive Impairment.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Plocabulin

    go.drugbank.com/drugs/DB13137
    Investigational

    PM060184 has been used in trials studying Solid Tumors.

    Categories: Heterocyclic Compounds, 1-Ring