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Arbaclofen
go.drugbank.com/drugs/DB08891InvestigationalIt has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord injury. … It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind
Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigationalin patients diagnosed with Haemophilia A. … [A38907] Also known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated with polyethylene glycol (PEG) to reduce the number of infusions necessary to prevent bleeds
Ouabain
go.drugbank.com/drugs/DB01092ApprovedIt is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase. … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis.
Categories: Compounds used in a research, industrial, or household settingFedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigationalFedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis. … [A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090]
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsSodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigationalacts as a highly selective potassium removing agent. … Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that
Categories: Compounds used in a research, industrial, or household settingLoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.
Products: TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML, TRANEXEL 250MG/5ML IV ENJEKSİYONLUK ÇÖZELTİCrofelemer
go.drugbank.com/drugs/DB04941ApprovedInvestigationalCrofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree <i>Croton lechleri</i>.
Categories: Compounds used in a research, industrial, or household settingPolythiazide
go.drugbank.com/drugs/DB01324ApprovedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Oxyphenonium
go.drugbank.com/drugs/DB00219ApprovedIt is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem] … A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine.
International brands: A-Spasm