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Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigationalIloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. … [A263316] Iloprost is available as an inhaled solution and intravenous formulations. It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151]
Synonyms: (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acid, (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acidProducts: VENTAVIS ®, İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPULSMAD family member 2
go.drugbank.com/bio_entities/BE0004445TargetHumansMay act as a tumor suppressor in colorectal carcinoma (PubMed:8752209) … Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription.
Synonyms: MAD homolog 2, Mad-related protein 2Oxcarbazepine
go.drugbank.com/drugs/DB00776ApprovedInvestigationalOxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000. … - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine].
Categories: P-glycoprotein inducers, P-glycoprotein substratesSynonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamideTechnetium Tc-99m succimer
go.drugbank.com/drugs/DB09436ApprovedTechnetium Tc-99m (<sup>99m</sup>Tc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular
Categories: Compounds used in a research, industrial, or household settingOlokizumab
go.drugbank.com/drugs/DB13127InvestigationalTargeting IL-6 function can be achieved directly, or through interrupting the IL-6 receptor or gp130 receptor axes. … Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system.
Quinestrol
go.drugbank.com/drugs/DB04575ApprovedThe 3-cyclopentyl ether of ethinyl estradiol.
Synonyms: Estradiol-17-beta 3-cyclopentyl ether, 17-alpha-Ethinylestradiol 3-cyclopentyl etherMethyl nicotinate
go.drugbank.com/drugs/DB13882ApprovedMethyl nicotinate is the methyl ester of [DB00627] that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. … The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(Carbomethoxy)pyridine, 3-(Methoxycarbonyl)pyridineHydroxyethyl cellulose
go.drugbank.com/drugs/DB11602ApprovedIt is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. … It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic
Salts: Hydroxyethyl cellulose (100 MPa.s at 2%), Hydroxyethyl cellulose (140 MPa.s at 5%)Categories: Compounds used in a research, industrial, or household settingAT2220
go.drugbank.com/drugs/DB05200InvestigationalGAA to the lysosome, where it can perform its normal function. … AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones.