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Displaying results 2471 - 2480 of 2744 in total
  1. Target

    Proteasome subunit beta type-1

    go.drugbank.com/bio_entities/BE0002347
    TargetHumans

    Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C5
  2. Drug

    Nafarelin

    go.drugbank.com/drugs/DB00666
    ApprovedInvestigational

    Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.

    Categories: Sex Hormones and Insulins
  3. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons...

    Categories: Sex Hormones and Insulins
  4. Drug

    Plosaracetam

    go.drugbank.com/drugs/DB21594
    Investigational

    The usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent.

  5. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist.

  6. Drug

    Olomorasib

    go.drugbank.com/drugs/DB21697
    Investigational

    The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.

  7. Drug

    Istisociclib

    go.drugbank.com/drugs/DB21703
    Investigational

    The usage of the INN stem '-ciclib' in the name indicates that Istisociclib is a cyclin dependant kinase inhibitor.

  8. Drug

    Atirmociclib

    go.drugbank.com/drugs/DB21733
    Investigational

    The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor.

  9. Drug

    Allogeneic processed thymus tissue

    go.drugbank.com/drugs/DB16736
    Approved

    Allogeneic processed thymus tissue implantation works by migrating the recipient’s bone marrow-derived stem cells to the implanted cultured thymus tissue that develops immunocompetent naïve T cells.

  10. Drug

    Declopramide

    go.drugbank.com/drugs/DB06421
    Experimental