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Displaying results 2481 - 2490 of 10000 in total
  1. Drug

    Anecortave

    go.drugbank.com/drugs/DB12081
    Experimental

    Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension).

  2. Drug

    YCT-529

    go.drugbank.com/drugs/DB21748
    Investigational

    YCT-529 is under investigation in clinical trial NCT06542237 (Open Label, Repeat Dose Study Evaluating YCT-529 in Healthy Males).

  3. Drug

    L-Glutamine

    go.drugbank.com/drugs/DB00130
    ApprovedInvestigationalNutraceutical

    It is the principal carrier of nitrogen in the body and is an important energy source for many cells. … An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease [L892]. This oral formulation is marketed under the tradename Endari by Emmaus Medical.

  4. Drug

    Pyruvic acid

    go.drugbank.com/drugs/DB00119
    ApprovedInvestigationalNutraceutical

    An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures.

  5. Drug

    ANZ-100

    go.drugbank.com/drugs/DB05967
    Investigational

  6. Drug

    Velpatasvir

    go.drugbank.com/drugs/DB11613
    ApprovedInvestigational

    Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].

  7. Drug

    Bamosiran

    go.drugbank.com/drugs/DB12256
    Investigational

    Bamosiran has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, and Open Angle Glaucoma.

  8. Drug

    Triamterene

    go.drugbank.com/drugs/DB00384
    Approved

    Triamterene is a weak antagonist of folic acid, and a photosensitizing drug.[L6163] Triamterene was approved by the Food and Drug Administration in the U.S. in 1964. … Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension.

    Categories: Decreased Renal K+ Excretion
  9. Target

    Nuclear receptor subfamily 0 group B member 1

    go.drugbank.com/bio_entities/BE0000074
    TargetHumans

    Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions (PubMed:12482977, PubMed

    Polypeptides: Nuclear receptor subfamily 0 group B member 1Synonyms: Nuclear receptor DAX-1
  10. Target

    Nuclear receptor subfamily 1 group D member 1

    go.drugbank.com/bio_entities/BE0009347
    TargetHumans

    Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. … Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced

    Polypeptides: Nuclear receptor subfamily 1 group D member 1