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Displaying results 241 - 250 of 3387 in total
  1. Drug

    Sacituzumab govitecan

    go.drugbank.com/drugs/DB12893
    ApprovedInvestigational

    [A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment.

  2. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent n...

    Mixtures: Se-Tan PLUS, Virt-PnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  3. Drug

    PCO-371

    go.drugbank.com/drugs/DB14946
    Investigational

    PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).

    Synonyms: non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I
  4. Drug

    Brenetafusp

    go.drugbank.com/drugs/DB19441
    Investigational

    Brenetafusp is under investigation in clinical trial NCT04262466 (Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors).

    Synonyms: Immunoglobulin, anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment VL-((GGGGS)4GGGS)-VH) fusion protein with peptide linker (GGGGS) fusion protein with T-cell receptor β chain
  5. Drug

    Botaretigene sparoparvovec

    go.drugbank.com/drugs/DB16814
    Investigational

    Synonyms: VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT
  6. Drug

    VEGFR 2 Kinase inhibitor I

    go.drugbank.com/drugs/DB17061
    Experimental

    Synonyms: Vegf receptor 2 kinase inhibitor i
  7. Drug

    Beludavimab

    go.drugbank.com/drugs/DB18952
    Investigational

    Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).

    Synonyms: IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL
  8. Drug

    Hydroxyethyl Starch

    go.drugbank.com/drugs/DB09106
    ApprovedInvestigational

    Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified acc...

    Mixtures: PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 1000 ML SETSIZ, PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 500 ML SETLI
  9. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMETASONFUROAT 1A PH 50UG
  10. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for ...

    Mixtures: Dex-Moxi PF, DexMoxiKetor PFCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors